Star Trek: Resurgence is a story-driven adventure game by Dramatic Labs, a studio created recently by former Telltale developers who wanted to carry on the tradition of games they were previously known for like The Walking Dead, The Wolf Among Us, and countless others. If you're familiar with any of those games then you should already know basically what to expect with Star Trek: Resurgence -- a lot of cutscenes where you pick dialogue options and react to timed prompts, alternating with moments of limited exploration, light puzzle-solving, and scripted action sequences, where the decisions you make along the way influence the way the story shapes up. The story, of course, is the main draw, here, with it basically being like a good multi-episode arc from the 90's era of Star Trek TV shows, expanded into a 10-12 hour runtime that allows you to really immerse yourself in the setting and feel like you're actually taking part in a series of Star Trek, in more elaborate and involved ways than what would typically be shown in the actual shows.
Now, you don't necessarily have to be a fan of Star Trek to enjoy Resurgence -- at a minimum, you just have to enjoy "choose your own adventure" style video games and be open to an optimistic sci-fi space adventure story, which requires no prior knowledge of Star Trek since it revolves around an entirely new cast of characters trying to resolve a conflict between two entirely made-up, new-to-this-game species. The game is sure to explain any relevant lore details from the shows or movies that a new player might not know, or that an established fan might have even forgotten about, while other things can be easily deduced as you go along; for example you don't need to know what the Kobayashi Maru is to infer from the surrounding context clues that it's a notoriously difficult test, which is all you really need to know to understand the point of that conversation. So it should be fairly easy to follow along with everything even if you don't know anything about Star Trek.
Now, you don't necessarily have to be a fan of Star Trek to enjoy Resurgence -- at a minimum, you just have to enjoy "choose your own adventure" style video games and be open to an optimistic sci-fi space adventure story, which requires no prior knowledge of Star Trek since it revolves around an entirely new cast of characters trying to resolve a conflict between two entirely made-up, new-to-this-game species. The game is sure to explain any relevant lore details from the shows or movies that a new player might not know, or that an established fan might have even forgotten about, while other things can be easily deduced as you go along; for example you don't need to know what the Kobayashi Maru is to infer from the surrounding context clues that it's a notoriously difficult test, which is all you really need to know to understand the point of that conversation. So it should be fairly easy to follow along with everything even if you don't know anything about Star Trek.